Product Name: 3-Methacryloxypropyltrimethoxysilane
Synonyms: γ-Methacryloxypropyltrimethoxysilane, A-174 Silane, Silquest A-174
Chemical Formula: C10H20O5Si
CAS Number: 2530-85-0
Recommended Use: Crosslinking agent in adhesives, sealants, surface treatment
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GHS Classification: Flammable liquid (Category 3), Skin irritation (Category 2), Eye irritation (Category 2A), Skin sensitization (Category 1)
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause allergic skin reaction, flammable liquid and vapor
Label Elements: Flame, exclamation mark
Precautionary Statements: Keep away from ignition sources, avoid breathing vapors, wash hands after handling, wear protective gloves/eye protection
Potential Health Effects: Irritation to skin, eyes, respiratory tract; can cause dermatitis on prolonged exposure; vapor inhalation may cause dizziness or headache
Environmental Hazards: May be harmful to aquatic life due to persistence of chemical in water bodies
Chemical Name: 3-Methacryloxypropyltrimethoxysilane
CAS Number: 2530-85-0
Purity: >97%
Impurities: Trimethoxysilane derivatives (<2%), Methacrylic acid resin residues (<1%)
Other Components: None known at significant concentrations
Inhalation: Move exposed person to fresh air, keep at rest, seek medical attention for respiratory symptoms like coughing or difficulty breathing
Skin Contact: Remove contaminated clothing, wash skin with soap and water for at least 15 minutes, consult physician if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, seek immediate medical attention for persistent irritation or vision changes
Ingestion: Rinse mouth, do not induce vomiting, call a poison control center or physician for guidance, never give anything by mouth to an unconscious person
Most Important Symptoms: Redness, blistering (skin); eye pain, tearing; difficulty breathing if vapors inhaled; dizziness
Notes for Physicians: Treat symptomatically; consider pulmonary irritation in severe inhalation cases
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, sand; water mist recommended for cooling exposed containers
Unsuitable Media: Water jet may spread material and increase fire risk
Special Hazards: Vapors may form explosive mixtures with air, combustion produces carbon oxides, silicon oxides, methanol fumes
Protective Equipment for Firefighters: Full protective clothing and self-contained breathing apparatus
Firefighting Procedures: Evacuate area, fight from a safe distance, prevent runoff to drains or watercourses, cool unopened containers exposed to heat with water spray
Personal Precautions: Evacuate unnecessary personnel, ventilate area, eliminate ignition sources, wear appropriate personal protective equipment
Environmental Precautions: Prevent spillage from entering drains, soil, surface water, inform authorities if material enters water systems
Cleanup Methods: Absorb with inert material (sand, earth, vermiculite), collect in chemical waste container, decontaminate area with detergent and plenty of water, dispose according to official regulations
Additional Advice: Avoid contact with eyes and skin during cleanup
Handling: Use in well-ventilated areas, ground/bond containers when transferring, avoid splashes and vapor formation, wash hands before breaks and after handling
Storage: Store tightly closed in cool, dry, well-ventilated area away from heat sources, incompatible chemicals (oxidizers, acids, water), keep away from direct sunlight, temperature below 30°C recommended
Specific Precautions: Use only non-sparking tools, take measures to prevent static discharge, keep container upright to avoid leaks
Incompatibilities: Strong oxidizing agents, moisture (hydrolyzes to form methanol)
Exposure Limits: Methanol (hydrolysis product) ACGIH TLV 200 ppm TWA, no specific limit for parent compound
Engineering Controls: Use local exhaust or general ventilation to maintain vapor levels below exposure limits, provide eyewash stations and safety showers
Personal Protection: Chemical-resistant gloves (nitrile, neoprene), protective goggles or face shield, flame-resistant lab coat, properly fitted respirator for high vapor concentrations
Hygiene Measures: Wash hands thoroughly after handling, do not eat, drink, or smoke in work area, remove contaminated clothing before entering eating areas
Environmental Controls: Prevent release to environment, use spill control materials and dispose of contaminated cleanup materials as hazardous waste
Appearance: Clear, colorless to pale yellow liquid
Odor: Mild, acrylate-like
Odor Threshold: Not established
pH: Neutral (not measured in water due to hydrolysis)
Melting Point: <-70°C
Boiling Point: ≈255°C (decomposes)
Flash Point: 88°C (closed cup)
Evaporation Rate: Not available
Flammability: Flammable liquid
Explosion Limits: Upper- 13.0 vol%, Lower- 1.8 vol% (based on methanol evolution)
Vapor Pressure: 0.4 mm Hg at 20°C
Vapor Density: 6.2 (air = 1)
Relative Density: 1.045 – 1.075 g/cm³ at 20°C
Solubility: Hydrolyzes in water; soluble in alcohols, esters, ketones
Partition Coefficient (n-octanol/water): Not determined
Auto-Ignition Temperature: ≈400°C
Decomposition Temperature: Not specified
Viscosity: 2-3 mPa·s at 25°C
Chemical Stability: Stable under recommended storage conditions, sensitive to moisture (hydrolyzes gradually)
Reactivity: Reacts with water and acids to form methanol; may polymerize upon storage above ambient temperature or in presence of light
Hazardous Reactions: Contact with oxidizing agents may cause violent reaction
Conditions to Avoid: Exposure to moisture, excessive heat, light, sources of ignition
Incompatible Materials: Strong acids, bases, oxidizing agents, amines, water
Hazardous Decomposition Products: Methanol, acrylate monomers, carbon monoxide, silicon oxides
Acute Toxicity: Oral LD50 (rat) 2260 mg/kg; estimated inhalation LC50 (rat, 4hr) >5000 mg/m³; skin LD50 (rabbit) >2000 mg/kg
Skin Corrosion/Irritation: Causes moderate skin irritation with redness
Serious Eye Damage/Irritation: Causes severe eye irritation, possible corneal injury
Respiratory or Skin Sensitization: May cause allergic skin reaction (sensitizer)
Germ Cell Mutagenicity: Not mutagenic in standard assays
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, ACGIH, or OSHA
Reproductive Toxicity: No data available for reproductive toxicity of parent compound; methanol (hydrolysis product) may be teratogenic
Specific Target Organ Toxicity: No data for repeated exposure; methanol exposure affects vision, nervous system
Aspiration Hazard: Not classified as aspiration hazard
Additional Information: Effects may be delayed for dermal and vapor exposure; sensitized individuals may show stronger skin reactions
Toxicity to Aquatic Organisms: LC50 (fish, 96 hr) >100 mg/L, EC50 (daphnia, 48 hr) >100 mg/L; methanol hydrolysis product is toxic to aquatic organisms
Persistence and Degradability: Product hydrolyzes in water, final products degrade slowly, persistent in absence of sunlight
Bioaccumulative Potential: Low bioconcentration factor expected; hydrolysis to methanol may increase risk
Mobility in Soil: High mobility expected before hydrolysis, may leach into groundwater
Other Adverse Effects: Release to environment should be avoided; may cause local contamination, especially in aquatic habitats
Waste Treatment Methods: Dispose of in accordance with local, state, and federal regulations as hazardous organic waste
Container Disposal: Empty containers should be triple-rinsed before disposal, never reuse for food or drink, puncture before landfill disposal if approved
Recommended Methods: Incineration with flue gas scrubbing, authorized chemical waste facility
Additional Advice: Do not pour into drains, surface water, or soil; collect small spills and residues with absorbent material for approved disposal
UN Number: 1993
Proper Shipping Name: Flammable Liquid, N.O.S. (3-Methacryloxypropyltrimethoxysilane)
Hazard Class: 3 (Flammable liquid)
Packing Group: III
Marine Pollutant: No
Transport Labels: Flammable Liquid, Class 3
Special Precautions: Keep containers securely closed, transport upright, segregate from incompatible substances, comply with local transport safety codes and international regulations
TSCA Inventory: Listed
REACH Registration: Registered in EU under REACH
SARA Title III: Not subject to reporting under Sections 302, 304, 313; methanol is listed SARA 313 (as product of hydrolysis)
OSHA: Hazardous by OSHA Hazard Communication Standard (29 CFR 1910.1200)
California Proposition 65: Methanol (as breakdown product) is listed as a reproductive toxin
WHMIS Classification: B3 (Flammable, combustible liquid); D2B (Toxic by skin/eye contact)
Other International Inventories: Australia (AICS): listed; Canada (DSL): listed; Japan (ENCS): listed; China (IECSC): listed
Label Requirement: Comply with all national and local chemical labeling and hazard communication laws
